Meat Lovers Pizza Bake

Featured in: Main Dishes

This meat-packed bake is a creative combo of pizza and casserole. Italian-seasoned meat sauce gets topped with melty cheese and dough brushed in olive oil. Then it's sprinkled with seasoning and baked till crisp. The result? Crisp, cheesy goodness over a hearty, tomato-based filling. Perfect for leftovers or feeding the whole family.
Twistytaste.com
Updated on Tue, 18 Mar 2025 18:06:15 GMT
Meat Lovers Pizza Bake Pin it
Meat Lovers Pizza Bake | twistytaste.com

This dish blends the best parts of pizza and casserole into one meat-packed treat. I first made it for a potluck and now everyone asks me to bring it again and again. It's got all those pizza flavors we crave but feels like good old home cooking. When I take a bite, it reminds me of my favorite pizza place but with that special homemade touch.

Throughout many family get-togethers, this has become our favorite comfort food. The way the cheese stretches into long strings and the smell fills up the house always gets everyone rushing to the kitchen before I can even pull it from the oven.

Must-Have Ingredient Guide

  • Ground beef: Go for 85% lean to get great taste without too much fat. Find fresh meat with a nice bright color
  • Italian sausage: This adds amazing flavor depth. You can pick mild or spicy based on what you like
  • Pepperoni: Try to get thick-cut, good quality slices for better bite and richer flavor
  • Mozzarella cheese: Shred it yourself for the smoothest melting. The pre-packaged stuff doesn't melt as nicely
  • Pizza sauce: Pick one with tomato and basil for that real pizza taste and thicker texture

Putting Your Casserole Together

Getting The Oven Ready:
Start by heating your oven to 425°F. This high heat will give you that crispy crust and perfectly melty cheese. While it's warming up, grab your 9x13 dish and coat it well with cooking spray, making sure to get the sides too.
Cooking The Meat:
Put a large skillet on medium-high heat. Brown your ground beef and sausage together, breaking it up as it cooks. Keep going until you don't see any pink, which takes about 8-10 minutes. Then drain off the extra fat so your casserole won't turn out greasy.
Adding Extra Flavor:
Toss your chopped pepperoni into the meat mix. Sprinkle flour and Italian seasoning over everything, and keep stirring so it doesn't clump up. This step makes a rich base that helps thicken your sauce just right.
Making The Sauce:
Now pour in the tomato basil sauce and mix it with your seasoned meat. Let it come to a gentle bubble, giving the flavors time to blend and the sauce time to thicken a bit. This takes around 5 minutes.
Putting It All Together:
Pour your meat sauce into the prepared dish and spread it out evenly. Cover it completely with a thick layer of mozzarella. Then carefully roll out the pizza dough on top, gently pulling it to reach all the edges.
Easy Meat Lovers Pizza Casserole Pin it
Easy Meat Lovers Pizza Casserole | twistytaste.com

My grandma from Italy always told me to let casseroles sit before serving. Being patient lets everything set up properly and keeps your serving from turning into a runny mess on the plate.

Ways To Serve It

This filling dish goes great with a crunchy Caesar salad and some warm garlic bread. For a complete dinner, add some roasted veggies on the side. If you want to get fancy, a glass of bold red wine really brings out all the rich flavors.

Fun Twists To Try

  • Spice things up by adding cooked mushrooms, sweet caramelized onions, or colorful roasted peppers between your meat and cheese
  • Switch up your cheeses with provolone or fontina for new flavor combos
  • Put some fresh basil under the pizza dough for a burst of garden flavor

Keeping It Fresh

Store any leftovers in the fridge with a cover for up to 4 days. When you want more, heat single portions in the oven at 350°F for 15 minutes to keep that crust crispy. Try not to use the microwave if you can help it - it'll make your crust get soggy.

Delicious Meat Lovers Pizza Casserole Pin it
Delicious Meat Lovers Pizza Casserole | twistytaste.com

This pizza casserole has become my go-to dish for gatherings, always getting tons of compliments and folks asking how I made it. The mix of three meats, stretchy cheese, and that crispy top creates a comfort food that nobody can turn down. It shows how combining two things we already love can make something even more amazing.

Frequently Asked Questions

→ Can I make this ahead of time?
Sure, prep the meat layer early. Just wait on the top crust until you're ready to bake so it stays fresh and crispy.
→ What are some swaps for pizza dough?
Crescent or biscuit dough works just as well if you don't have pizza dough on hand.
→ What's a good way to add veggies?
Toss in sautéed peppers, onions, or mushrooms with the meat mixture for more flavor and nutrients.
→ How do I store the leftovers?
Keep them in the fridge (covered) for up to three days. Reheat in the oven to keep the crust nice and crisp.
→ Can this be frozen?
Yes, but freeze it before adding the crust. The dough is best when fresh right before baking.

Meat Lovers Pizza Bake

Packed with three meats, mozzarella, and a soft crust that bakes golden, this dish mixes pizza and pasta flavors in every bite.

Prep Time
15 Minutes
Cook Time
25 Minutes
Total Time
40 Minutes

Category: Main Dishes

Difficulty: Intermediate

Cuisine: Italian-American

Yield: 8 Servings

Dietary: ~

Ingredients

→ Protein Base

01 1 pound pork sausage
02 1 cup pepperoni, cut into small chunks
03 1 pound ground beef, lean

→ Sauces & Spices

04 4 teaspoons split Italian seasoning
05 1 (26-ounce) jar tomato basil pasta sauce
06 1/4 cup plain white flour, used to thicken the sauce

→ Toppings

07 1 tablespoon olive oil for brushing
08 3 tablespoons grated fresh Parmesan cheese
09 2 cups shredded mozzarella, used in portions
10 1 (13.8-ounce) can of pizza dough from the fridge

Instructions

Step 01

Preheat your oven to a toasty 425°F. Give a light coating of cooking spray to a 9x13-inch dish so cleanup later is a breeze.

Step 02

Take a big pan and cook the ground beef along with the sausage on medium-high heat until they’re thoroughly browned. Remove any leftover grease so the final dish isn’t oily.

Step 03

Add the chopped pepperoni, flour, and 3 teaspoons of the spice mix to the meat blend in the pan. Then, pour in the jar of pasta sauce and warm it up until it’s bubbling gently.

Step 04

Move your meat sauce to the dish you prepped. Sprinkle over 1½ cups of the mozzarella as a blanket. Unroll the pizza dough and gently place it over the cheese.

Step 05

Coat the pizza dough with olive oil, then scatter the last of the spice blend, mozzarella, and Parmesan cheese on top. It’ll make the crust wonderfully crisp and golden.

Step 06

Place the dish in the heated oven and let it cook for 20 to 25 minutes until the crust is golden brown and the cheese is gooey and bubbling.

Notes

  1. This filling bake blends all the bold tastes of a loaded pizza with the coziness of a casserole.
  2. Loaded with three kinds of meat, this dish is a flavor-packed option for meat lovers.
  3. The two-cheese combination guarantees a melted, golden topping everyone will enjoy.

Tools You'll Need

  • A dish measuring 9x13 inches
  • Large frying pan or skillet
  • Spoons for mixing
  • Brush for applying oil (pastry or similar)

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Includes dairy from mozzarella and Parmesan cheeses
  • Includes gluten due to flour and the dough used

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 520
  • Total Fat: 32 g
  • Total Carbohydrate: 28 g
  • Protein: 35 g