Mac Cheese Meatloaf Casserole

Featured in: Main Dishes

This dish packs cheesy macaroni on top of sweet saucy meatloaf—kind of like rolling two dinners into one pan. Sharp cheddar melts over the whole thing and the ground beef underneath soaks up those BBQ flavors. It’s simple and everyone wants seconds.

Twistytaste.com
Updated on Mon, 19 May 2025 17:21:40 GMT
Cheesy baked mac with ground beef and parsley on a white plate. Pin it
Cheesy baked mac with ground beef and parsley on a white plate. | twistytaste.com

Ultimate Mac and Cheese Meatloaf Comfort

One cold night my kids wanted both mac and cheese and meatloaf. So we just went wild and mixed them into a single, super tasty dish. This became our family favorite right away. You get a yummy, flavorful meatloaf base with creamy cheesy pasta piled on top. We can't get enough around the dinner table.

A Crowd-Pleaser Every Time

This casserole totally wins because of those tasty layers. Savory meatloaf topped with melty, cheesy pasta is just perfection. It's a lifesaver meal for hectic evenings and everyone leaves the table happy and full. Plus leftovers? They're somehow even yummier the next day.

All You Need To Grab

  • Macaroni Noodles: Can't have that cheesy topping without pasta.
  • Shredded Mozzarella and Cheddar: Cheese overload is the best kind.
  • Lipton Onion Soup Mix: Adds big flavor with almost zero effort.
  • Ketchup and Barbecue Sauce: My pick is Sweet Baby Rays for that finish on top.
  • Eggs: Help hold that meatloaf together just right.
  • Spices: Go simple so the flavors really shine.
  • Milk and Cheddar Cheese Soup: For thick, silky sauce you'll want to lick off the spoon.
  • Ritz Crackers: Trust me, these make meatloaf extra tasty.
  • Ground Beef: Lean is best for flavor without the grease.

Time To Cook

Serve:
Let the casserole settle, then dive in for some cheesy comfort.
Assemble Casserole:
Spoon that creamy pasta over the almost-done meatloaf, toss on more cheese, then finish baking till it's golden and bubbling.
Make Cheese Sauce:
Whip up the sauce, stir in your cooked noodles, and get ready for layering.
Cook Macaroni:
Boil your noodles while the meatloaf is getting started in the oven.
Prepare Meatloaf:
Mix up your meatloaf, press it into your dish, slather with sauce, and pop it in to bake first.

My Favorite Cooking Tricks

Make sure your meatloaf mix is spread out nice and even for super good slices. Grate your cheese fresh so it melts in perfectly. Don't overdo the noodles—you want them just right. Letting everything chill for a few minutes after baking makes it much easier to dish up.

Leftovers For Days

This meal keeps really well in the fridge for around three days, or you can stash extras in the freezer for as long as three months. Reheat in the oven for the best bite, but the microwave does the job fast if you're starving.

Easy Ways To Change It

Go wild and use your go-to barbecue sauce, or try breadcrumbs instead of Ritz for a change. Sneak in some sautéed veggies if you're feeling healthy—my crew never complains. Mix up the cheese with sharp cheddar or Monterey Jack for a new twist.

What To Serve It With

This is awesome next to a crisp salad or fresh steamed broccoli for a little balance. If I'm feeling fancy, I'll bake some garlic bread or a batch of cornbread. These sides just turn it into a full-blown feast.

Glass pan packed with gooey mac and cheese on a beefy layer. Pin it
Glass pan packed with gooey mac and cheese on a beefy layer. | twistytaste.com

Frequently Asked Questions

→ Can I freeze this casserole?

Yep, you can freeze it and it’ll last around 3 months. Just let it thaw in the fridge overnight, then pop it in the oven covered till warm. Take the foil off near the end to crisp up the cheese on top.

→ Can I make this casserole ahead of time?

Sure thing—you can cook the beef and mac in advance. Just stack ‘em together when ready, then bake till hot and melty. If starting cold, add a few extra minutes to the baking time.

→ Why do you add barbecue sauce to the meatloaf?

That BBQ sauce, especially Sweet Baby Ray’s Hickory & Brown Sugar, gives the meat a hint of smokiness and sweetness. Seriously levels up the flavors. Blend in more or less depending on what you like.

→ My mac and cheese seems too runny - what went wrong?

Don’t stress! It’ll get thicker once it sits for a bit after baking. Stick to the right amounts for milk and cheese. If it still feels too thin, just toss in some extra cheese and let it rest longer after coming out of the oven.

→ What can I substitute for Ritz crackers in the meatloaf?

No Ritz? No worries. Plain breadcrumbs, crushed up saltines, or a few quick oats do the trick just fine. Use about the same amount and your meatloaf will still hold together and stay nice and moist.

Mac Cheese Meatloaf Casserole

Layers of gooey mac and cheese snuggle up on a tender beef meatloaf base. It’s total comfort with every bite.

Prep Time
18 Minutes
Cook Time
50 Minutes
Total Time
68 Minutes

Category: Main Dishes

Difficulty: Intermediate

Cuisine: American

Yield: 8 Servings (1 casserole)

Dietary: ~

Ingredients

01 30 crushed Ritz crackers.
02 2 lbs of ground beef, lean.
03 2 packets (2 oz) of Lipton onion soup mix.
04 1 cup of Sweet Baby Ray's barbecue sauce, Hickory & Brown Sugar flavor.
05 1 cup of ketchup.
06 2 eggs, whole.
07 10.5 oz condensed cheddar cheese soup.
08 2 cups milk.
09 3 cups macaroni pasta.
10 1 tbsp of onion powder.
11 1 tbsp garlic powder.
12 1 tsp black pepper.
13 1 tsp salt.
14 4 cups shredded cheese blend (mozzarella and cheddar).

Instructions

Step 01

Set your oven to 350°F, and stir together barbecue sauce with ketchup in a bowl.

Step 02

Mix ground beef, eggs, crushed crackers, onion soup mix, and half the sauce blend in a big bowl.

Step 03

Grease a 9x13 pan, press the meat mixture into it, and spread the leftover sauce on top.

Step 04

Pop the pan in the oven and bake for half an hour.

Step 05

Cook macaroni as the package instructions guide you.

Step 06

Combine soup with milk and blend it until creamy, then throw in the spices.

Step 07

Toss the cooked pasta and 2 cups of shredded cheese with the milk mixture.

Step 08

Spread the mac and cheese mixture over your partly baked meatloaf.

Step 09

Sprinkle the last 2 cups of shredded cheese across the top.

Step 10

Bake for another 17-20 mins until you see the cheese melt and brown slightly.

Step 11

Give it a few minutes to cool down before slicing and serving.

Notes

  1. A feel-good meal everyone craves.
  2. Make it today, eat it tomorrow—it holds up great.
  3. You can freeze leftovers easily.
  4. Awesome choice for family-style dinners.
  5. Leftovers heat up perfectly.

Tools You'll Need

  • A 9x13 pan for baking.
  • Big bowls for mixing.
  • Standard measuring cups.
  • Pot for cooking pasta.
  • A rolling pin to crush crackers.

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains dairy (milk, cheese).
  • Includes eggs.
  • Gluten present (pasta, crackers).

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 549
  • Total Fat: 22 g
  • Total Carbohydrate: 40 g
  • Protein: 45 g